Drug metabolism in pH 7.5 HEPES buffer assessed as porcine liver esterase-mediated compound hydrolysis measured up to 72 hrs by HPLC analysis

Basic Information

ID: ALA4808766

Type: ADME

Description: Drug metabolism in pH 7.5 HEPES buffer assessed as porcine liver esterase-mediated compound hydrolysis measured up to 72 hrs by HPLC analysis

Format: BAO_0000221

Organism: Sus scrofa

Tissue: Liver

Target: Carboxylesterase(ALA3383)

Document: ALA4808172

Drug metabolism in pH 7.5 HEPES buffer assessed as porcine liver esterase-mediated compound hydrolysis measured up to 72 hrs by HPLC analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4808766

Drug degradation

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
602.65	7.16	7.16
574.56	6.58	6.58

Parent Molecular Weight

ALogP

Polar Surface Area

602.65

7.16

574.56

6.58

Drug metabolism in pH 7.5 HEPES buffer assessed as porcine liver esterase-mediated compound hydrolysis measured up to 72 hrs by HPLC analysis

Basic Information

Activity Charts

Compound Summary