Basic Information
ID: ALA4808842
Type: Binding
Description: Inhibition of recombinant full length GST-tagged PDE5A1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as substrate incubated for 1.5 hrs by IMAP-FP assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4808842
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.38 | 3.51 | 3.51 |
| 474.59 | 1.61 | 1.61 |
| 402.45 | 4.76 | 4.76 |
| 352.43 | 4.75 | 4.75 |
| 432.48 | 4.77 | 4.77 |
| 402.45 | 4.76 | 4.76 |
| 390.41 | 4.89 | 4.89 |
| 336.44 | 5.05 | 5.05 |
| 372.42 | 4.75 | 4.75 |
| 388.42 | 4.45 | 4.45 |
| 384.44 | 4.53 | 4.53 |
| 370.42 | 4.89 | 4.89 |
| 416.43 | 4.48 | 4.48 |
| 402.45 | 4.76 | 4.76 |
| 386.45 | 5.06 | 5.06 |
| 400.43 | 4.37 | 4.37 |
| 402.44 | 5.42 | 5.42 |
| 436.58 | 4.88 | 4.88 |
| 390.41 | 5.76 | 5.76 |
| 441.31 | 6.06 | 6.06 |
| 354.43 | 5.19 | 5.19 |
| 378.47 | 5.28 | 5.28 |
| 451.32 | 5.51 | 5.51 |
| 448.52 | 6.42 | 6.42 |
| 390.41 | 4.89 | 4.89 |
| 386.45 | 5.06 | 5.06 |
| 370.42 | 4.89 | 4.89 |
| 468.60 | 4.75 | 4.75 |
| 417.42 | 4.66 | 4.66 |
| 361.40 | 4.08 | 4.08 |
| 399.49 | 4.80 | 4.80 |
| 362.39 | 4.34 | 4.34 |
| 398.46 | 4.92 | 4.92 |
| 386.88 | 5.40 | 5.40 |
| 441.58 | 5.89 | 5.89 |
| 388.41 | 5.03 | 5.03 |
| 454.57 | 4.44 | 4.44 |
| 388.42 | 4.45 | 4.45 |
| 464.52 | 6.54 | 6.54 |
| 390.41 | 4.89 | 4.89 |
| 406.87 | 5.40 | 5.40 |
| 336.39 | 4.11 | 4.11 |
| 373.41 | 4.14 | 4.14 |
| 429.52 | 4.08 | 4.08 |
| 422.48 | 5.90 | 5.90 |
| 386.45 | 5.06 | 5.06 |
| 452.57 | 4.58 | 4.58 |
| 388.41 | 5.03 | 5.03 |
| 416.48 | 5.15 | 5.15 |
| 452.57 | 4.58 | 4.58 |
| 406.40 | 5.64 | 5.64 |
| 350.42 | 4.50 | 4.50 |
| 482.58 | 4.90 | 4.90 |
| 427.55 | 5.58 | 5.58 |
| 388.41 | 5.03 | 5.03 |
| 404.44 | 5.20 | 5.20 |
| 451.32 | 5.51 | 5.51 |
| 469.03 | 5.09 | 5.09 |
| 358.39 | 5.02 | 5.02 |
| 455.56 | 4.83 | 4.83 |
| 406.87 | 5.40 | 5.40 |
| 416.48 | 5.15 | 5.15 |
| 486.59 | 4.89 | 4.89 |
| 407.56 | 5.58 | 5.58 |
| 378.45 | 4.81 | 4.81 |
| 406.87 | 5.40 | 5.40 |
| 470.56 | 4.71 | 4.71 |
| 470.56 | 4.71 | 4.71 |
| 388.42 | 4.45 | 4.45 |
| 370.41 | 4.91 | 4.91 |
| 434.58 | 4.44 | 4.44 |
| 390.41 | 4.89 | 4.89 |
| 484.59 | 5.10 | 5.10 |
| 425.55 | 5.72 | 5.72 |
| 470.56 | 4.71 | 4.71 |