Basic Information
ID: ALA4809521
Type: Functional
Description: Antiarrhythmic activity in patient-derived hiPSC-CMs carrying LQT3 mutation assessed as shortening of action potential duration
Organism: Homo sapiens
Cell type: iPSC-CM
Activity Charts
Bioactivity
Activity Types for Assay ALA4809521
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 179.26 | 2.03 | 2.03 |
| 179.26 | 2.03 | 2.03 |
| 179.26 | 2.03 | 2.03 |
| 257.80 | 3.06 | 3.06 |
| 277.80 | 3.38 | 3.38 |
| 255.67 | 2.43 | 2.43 |
| 255.67 | 2.43 | 2.43 |
| 333.74 | 3.66 | 3.66 |
| 305.85 | 4.03 | 4.03 |
| 323.66 | 3.45 | 3.45 |
| 215.72 | 2.03 | 2.03 |
| 263.77 | 3.07 | 3.07 |
| 305.85 | 3.86 | 3.86 |
| 335.88 | 3.66 | 3.66 |
| 291.82 | 3.69 | 3.69 |
| 335.88 | 3.66 | 3.66 |
| 291.82 | 4.18 | 4.18 |
| 241.76 | 2.42 | 2.42 |
| 257.80 | 3.07 | 3.07 |
| 443.82 | 5.08 | 5.08 |
| 257.76 | 2.21 | 2.21 |
| 229.75 | 2.29 | 2.29 |
| 319.88 | 4.42 | 4.42 |
| 345.79 | 4.40 | 4.40 |
| 299.80 | 3.92 | 3.92 |
| 319.83 | 3.50 | 3.50 |
| 201.70 | 1.72 | 1.72 |
| 243.78 | 2.68 | 2.68 |
| 241.76 | 2.42 | 2.42 |
| 277.80 | 3.38 | 3.38 |
| 317.74 | 3.78 | 3.78 |
| 291.82 | 3.64 | 3.64 |
| 277.80 | 3.38 | 3.38 |
| 283.37 | 3.56 | 3.56 |
| 201.70 | 1.72 | 1.72 |
| 321.85 | 3.01 | 3.01 |
| 241.76 | 2.42 | 2.42 |
| 333.90 | 4.81 | 4.81 |
| 299.84 | 2.70 | 2.70 |
| 327.86 | 4.54 | 4.54 |
| 273.80 | 2.31 | 2.31 |
| 279.77 | 2.77 | 2.77 |
| 317.74 | 3.78 | 3.78 |
| 319.88 | 3.90 | 3.90 |
| 299.80 | 3.92 | 3.92 |
| 307.82 | 3.39 | 3.39 |
| 229.75 | 2.37 | 2.37 |
| 271.83 | 3.46 | 3.46 |
| 277.80 | 3.38 | 3.38 |
| 277.80 | 3.33 | 3.33 |
| 385.74 | 4.80 | 4.80 |
| 429.79 | 4.43 | 4.43 |
| 217.70 | 1.42 | 1.42 |
| 291.82 | 3.72 | 3.72 |
| 283.84 | 3.59 | 3.59 |
| 277.80 | 3.38 | 3.38 |
| 345.44 | 4.85 | 4.85 |
| 241.76 | 2.42 | 2.42 |
| 263.77 | 3.07 | 3.07 |
| 347.76 | 3.71 | 3.71 |
| 215.72 | 1.98 | 1.98 |