Inhibition of eNOS in Wistar rat endothelium-intact thoracic aortic rings assessed as inhibition of acetylcholine-evoked relaxation at 20 uM pretreate...

Basic Information

ID: ALA4809869

Type: ADME

Description: Inhibition of eNOS in Wistar rat endothelium-intact thoracic aortic rings assessed as inhibition of acetylcholine-evoked relaxation at 20 uM pretreated with compound for 30 mins followed by norepinephrine addition and later incubated with acetylcholine

Format: BAO_0000221

Organism: Rattus norvegicus

Strain: Wistar

Tissue: Thoracic aorta

Target:  Nitric oxide synthase, endothelial(ALA1075230)

Document:  ALA4808198

Inhibition of eNOS in Wistar rat endothelium-intact thoracic aortic rings assessed as inhibition of acetylcholine-evoked relaxation at 20 uM pretreated with compound for 30 mins followed by norepinephrine addition and later incubated with acetylcholine: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
367.373.333.33