Basic Information
ID: ALA4809906
Type: ADME
Description: Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD1/BD2 Y390A mutant (1 to 477 residue) (unknown origin) measured after 30 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4809906
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.37 | 1.15 | 1.15 |
| 414.48 | 3.96 | 3.96 |
| 339.16 | 2.16 | 2.16 |
| 339.40 | 1.71 | 1.71 |
| 364.41 | 1.63 | 1.63 |
| 378.43 | 2.92 | 2.92 |
| 390.44 | 1.89 | 1.89 |
| 362.43 | 2.62 | 2.62 |
| 386.88 | 1.89 | 1.89 |
| 323.40 | 2.17 | 2.17 |
| 353.42 | 2.32 | 2.32 |
| 365.43 | 1.53 | 1.53 |
| 367.45 | 2.07 | 2.07 |
| 269.30 | 1.13 | 1.13 |
| 362.43 | 2.65 | 2.65 |
| 311.38 | 2.17 | 2.17 |
| 395.46 | 1.68 | 1.68 |
| 379.46 | 2.09 | 2.09 |
| 270.29 | 1.73 | 1.73 |
| 339.40 | 1.71 | 1.71 |
| 323.40 | 2.49 | 2.49 |
| 353.42 | 1.94 | 1.94 |
| 348.41 | 2.41 | 2.41 |
| 351.41 | 1.41 | 1.41 |
| 339.40 | 1.66 | 1.66 |
| 367.41 | 0.90 | 0.90 |
| 412.49 | 1.24 | 1.24 |
| 379.46 | 2.09 | 2.09 |
| 323.40 | 2.49 | 2.49 |
| 390.44 | 1.86 | 1.86 |
| 226.28 | 2.03 | 2.03 |
| 297.36 | 1.78 | 1.78 |
| 381.43 | 1.55 | 1.55 |
| 349.39 | 1.80 | 1.80 |
| 283.33 | 1.39 | 1.39 |
| 309.37 | 1.92 | 1.92 |
| 365.43 | 1.97 | 1.97 |
| 325.37 | 1.16 | 1.16 |
| 365.43 | 1.53 | 1.53 |
| 325.37 | 1.42 | 1.42 |
| 339.40 | 1.29 | 1.29 |
| 297.36 | 1.73 | 1.73 |
| 353.42 | 1.70 | 1.70 |