Inhibition of AChE in human erythrocytes using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate additi...

Basic Information

ID: ALA4811142

Type: Binding

Description: Inhibition of AChE in human erythrocytes using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured after 30 mins by Ellman's method

Format: BAO_0000219

Organism: Homo sapiens

Cell type: Erythrocyte

Target: Acetylcholinesterase(ALA220)

Document: ALA4808254

Inhibition of AChE in human erythrocytes using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured after 30 mins by Ellman's method: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4811142

IC50

Total(16)

Parent Molecular Weight	ALogP	Polar Surface Area
379.50	4.36	4.36
368.43	2.77	2.77
326.35	2.17	2.17
365.39	2.65	2.65
370.41	2.57	2.57
352.43	2.76	2.76
382.46	2.77	2.77
393.44	2.37	2.37
374.82	3.21	3.21
382.46	2.77	2.77
340.38	2.56	2.56
370.42	2.90	2.90
427.89	3.02	3.02
386.88	3.41	3.41
423.47	2.38	2.38
370.42	2.90	2.90

Parent Molecular Weight

ALogP

Polar Surface Area

379.50

4.36

368.43

2.77

326.35

2.17

365.39

2.65

370.41

2.57

352.43

2.76

382.46

2.77

393.44

2.37

374.82

3.21

382.46

2.77

340.38

2.56

370.42

2.90

427.89

3.02

386.88

3.41

423.47

2.38

370.42

2.90

Inhibition of AChE in human erythrocytes using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate additi...

Basic Information

Activity Charts

Compound Summary