Basic Information
ID: ALA4811365
Type: ADME
Description: Inhibition of human HDAC1 (1 to 482 reidue) expressed in sf9 cells using ZMAL(Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition and measured after 20 mins by fluorimetric method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Histone deacetylase 1(ALA325)
Document: ALA4811216
Inhibition of human HDAC1 (1 to 482 reidue) expressed in sf9 cells using ZMAL(Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition and measured after 20 mins by fluorimetric method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4811365
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 324.16 | 4.30 | 4.30 |
| 305.79 | 4.01 | 4.01 |
| 351.83 | 3.52 | 3.52 |