Basic Information
ID: ALA4811984
Type: Binding
Description: Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as fold reduction in vincristine IC50 at 20 uM measured after 72 hrs by CCK8 assay relative to vincristine IC50 alone
Organism: Homo sapiens
Cell type: KB/VCR
Activity Charts
Bioactivity
Activity Types for Assay ALA4811984
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.59 | 3.62 | 3.62 |
| 458.55 | 4.08 | 4.08 |
| 516.59 | 3.62 | 3.62 |
| 662.73 | 4.86 | 4.86 |
| 574.62 | 3.16 | 3.16 |
| 574.62 | 3.16 | 3.16 |
| 542.53 | 0.02 | 0.02 |
| 484.50 | 0.48 | 0.48 |
| 500.50 | -0.55 | -0.55 |
| 637.68 | 3.85 | 3.85 |
| 542.53 | 0.02 | 0.02 |
| 490.55 | 2.02 | 2.02 |
| 630.73 | 4.72 | 4.72 |
| 662.73 | 4.86 | 4.86 |