Basic Information
ID: ALA4811985
Type: Binding
Description: Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as potentiation of vincristine-induced antiproliferative activity by measuring vincristine IC50 at 2 uM measured after 72 hrs by CCK8 assay (Rvb = 0.51 uM)
Organism: Homo sapiens
Cell type: KB/VCR
Activity Charts
Bioactivity
Activity Types for Assay ALA4811985
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.59 | 3.62 | 3.62 |
| 520.62 | 5.37 | 5.37 |
| 546.66 | 5.77 | 5.77 |
| 458.55 | 4.08 | 4.08 |
| 516.59 | 3.62 | 3.62 |
| 662.73 | 4.86 | 4.86 |
| 574.62 | 3.16 | 3.16 |
| 574.62 | 3.16 | 3.16 |
| 688.74 | 5.32 | 5.32 |
| 542.53 | 0.02 | 0.02 |
| 484.50 | 0.48 | 0.48 |
| 620.70 | 4.29 | 4.29 |
| 500.50 | -0.55 | -0.55 |
| 578.66 | 4.91 | 4.91 |
| 620.70 | 4.29 | 4.29 |
| 637.68 | 3.85 | 3.85 |
| 542.53 | 0.02 | 0.02 |
| 490.55 | 2.02 | 2.02 |
| 604.70 | 5.31 | 5.31 |
| 630.73 | 4.72 | 4.72 |
| 662.73 | 4.86 | 4.86 |