Basic Information
ID: ALA4812133
Type: Toxicity
Description: Selectivity index, ratio of CC50 for human MRC-5 SV2 cells to IC50 for antitrypanosomal activity against nifurtimox-sensitive Trypanosoma cruzi Tulahuen CL2 infected in human MRC-5 SV2 cells
Activity Charts
Bioactivity
Activity Types for Assay ALA4812133
Ratio CC50/IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 135.13 | -0.06 | -0.06 |
| 136.11 | 0.06 | 0.06 |
| 268.23 | -2.27 | -2.27 |
| 393.14 | -1.38 | -1.38 |
| 267.25 | -1.98 | -1.98 |
| 377.79 | 0.34 | 0.34 |
| 348.13 | -0.24 | -0.24 |
| 421.84 | 0.74 | 0.74 |
| 445.79 | 1.36 | 1.36 |
| 335.24 | -0.96 | -0.96 |
| 367.37 | -0.58 | -0.58 |
| 373.37 | -0.30 | -0.30 |
| 346.14 | -1.22 | -1.22 |
| 309.33 | -0.86 | -0.86 |
| 310.27 | -2.88 | -2.88 |
| 344.33 | -0.92 | -0.92 |
| 388.34 | -0.40 | -0.40 |
| 395.78 | 0.48 | 0.48 |
| 330.14 | -0.19 | -0.19 |
| 317.25 | -1.04 | -1.04 |
| 391.82 | 0.65 | 0.65 |
| 291.27 | -2.00 | -2.00 |
| 292.26 | -2.11 | -2.11 |
| 411.34 | 0.71 | 0.71 |
| 363.40 | 0.06 | 0.06 |
| 349.37 | -0.25 | -0.25 |
| 371.40 | -0.19 | -0.19 |
| 395.78 | 0.48 | 0.48 |
| 427.34 | 0.59 | 0.59 |
| 344.33 | -0.92 | -0.92 |
| 363.40 | 0.06 | 0.06 |
| 369.38 | 0.19 | 0.19 |
| 412.23 | 0.99 | 0.99 |
| 361.33 | -0.17 | -0.17 |
| 407.81 | 0.35 | 0.35 |
| 214.03 | 0.70 | 0.70 |
| 368.35 | -0.44 | -0.44 |
| 282.26 | -2.40 | -2.40 |
| 330.14 | -0.19 | -0.19 |
| 307.31 | -0.95 | -0.95 |
| 334.30 | -2.19 | -2.19 |
| 357.37 | 0.00 | 0.00 |
| 361.79 | 1.37 | 1.37 |
| 347.34 | -1.58 | -1.58 |
| 391.82 | 0.65 | 0.65 |
| 343.34 | -0.31 | -0.31 |
| 379.32 | -0.03 | -0.03 |
| 281.27 | -1.67 | -1.67 |
| 324.30 | -2.62 | -2.62 |
| 413.77 | 0.62 | 0.62 |
| 412.23 | 0.99 | 0.99 |
| 383.82 | 0.40 | 0.40 |
| 361.79 | 1.37 | 1.37 |
| 301.69 | -1.33 | -1.33 |
| 296.29 | -2.52 | -2.52 |