Basic Information
ID: ALA4812134
Type: Functional
Description: Antileishmanial activity against amastigote form of Leishmania infantum MHOM/MA(BE)/67 infected in Swiss mouse peritoneal macrophages assessed as reduction in parasite growth treated at 2 hrs post-infection and measured after 5 days by Giemsa staining based microscopic analysis
Organism: Leishmania infantum
Strain: MHOM/MA(BE)/67
Cell type: Peritoneal macrophage
Activity Charts
Bioactivity
Activity Types for Assay ALA4812134
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.58 | 5.68 | 5.68 |
| 135.13 | -0.06 | -0.06 |
| 136.11 | 0.06 | 0.06 |
| 268.23 | -2.27 | -2.27 |
| 393.14 | -1.38 | -1.38 |
| 267.25 | -1.98 | -1.98 |
| 377.79 | 0.34 | 0.34 |
| 347.12 | -1.51 | -1.51 |
| 348.13 | -0.24 | -0.24 |
| 421.84 | 0.74 | 0.74 |
| 349.12 | -0.53 | -0.53 |
| 296.29 | -1.94 | -1.94 |
| 445.79 | 1.36 | 1.36 |
| 335.24 | -0.96 | -0.96 |
| 367.37 | -0.58 | -0.58 |
| 400.40 | -1.05 | -1.05 |
| 373.37 | -0.30 | -0.30 |
| 346.14 | -1.22 | -1.22 |
| 293.28 | -1.34 | -1.34 |
| 309.33 | -0.86 | -0.86 |
| 310.27 | -2.88 | -2.88 |
| 359.34 | -0.19 | -0.19 |
| 344.33 | -0.92 | -0.92 |
| 388.34 | -0.40 | -0.40 |
| 395.78 | 0.48 | 0.48 |
| 330.14 | -0.19 | -0.19 |
| 307.31 | -1.10 | -1.10 |
| 317.25 | -1.04 | -1.04 |
| 402.80 | 0.21 | 0.21 |
| 391.82 | 0.65 | 0.65 |
| 270.22 | -1.29 | -1.29 |
| 386.37 | -0.73 | -0.73 |
| 291.27 | -2.00 | -2.00 |
| 251.25 | -0.95 | -0.95 |
| 292.26 | -2.11 | -2.11 |
| 411.34 | 0.71 | 0.71 |
| 363.40 | 0.06 | 0.06 |
| 349.37 | -0.25 | -0.25 |
| 371.40 | -0.19 | -0.19 |
| 395.78 | 0.48 | 0.48 |
| 399.45 | 0.98 | 0.98 |
| 252.23 | -1.24 | -1.24 |
| 427.34 | 0.59 | 0.59 |
| 344.33 | -0.92 | -0.92 |
| 269.24 | -1.00 | -1.00 |
| 363.40 | 0.06 | 0.06 |
| 335.28 | -2.80 | -2.80 |
| 369.38 | 0.19 | 0.19 |
| 412.23 | 0.99 | 0.99 |
| 361.33 | -0.17 | -0.17 |
| 251.25 | -0.95 | -0.95 |
| 407.81 | 0.35 | 0.35 |
| 295.30 | -1.42 | -1.42 |
| 214.03 | 0.70 | 0.70 |
| 368.35 | -0.44 | -0.44 |
| 282.26 | -2.40 | -2.40 |
| 330.14 | -0.19 | -0.19 |
| 307.31 | -0.95 | -0.95 |
| 334.30 | -2.19 | -2.19 |
| 336.35 | -1.38 | -1.38 |
| 357.37 | 0.00 | 0.00 |
| 215.01 | 0.82 | 0.82 |
| 361.79 | 1.37 | 1.37 |
| 347.34 | -1.58 | -1.58 |
| 391.82 | 0.65 | 0.65 |
| 343.34 | -0.31 | -0.31 |
| 379.32 | -0.03 | -0.03 |
| 393.79 | 0.47 | 0.47 |
| 364.36 | -1.74 | -1.74 |
| 281.27 | -1.67 | -1.67 |
| 324.30 | -2.62 | -2.62 |
| 503.91 | 1.75 | 1.75 |
| 366.38 | -2.15 | -2.15 |
| 413.77 | 0.62 | 0.62 |
| 331.13 | -0.48 | -0.48 |
| 412.23 | 0.99 | 0.99 |
| 383.82 | 0.40 | 0.40 |
| 361.79 | 1.37 | 1.37 |
| 301.69 | -1.33 | -1.33 |
| 296.29 | -2.52 | -2.52 |