Basic Information
ID: ALA4812396
Type: Binding
Description: Inhibition of IDH1 R132H mutant (unknown origin) expressed in human U87 cells assessed as R-2-hydroxyglutarate production at 500 nM after 48 hrs by LC-MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: U87
Target: Isocitrate dehydrogenase [NADP] cytoplasmic(ALA2007625)
Document: ALA4811250
Inhibition of IDH1 R132H mutant (unknown origin) expressed in human U87 cells assessed as R-2-hydroxyglutarate production at 500 nM after 48 hrs by LC-MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4812396
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 593.58 | 6.97 | 6.97 |
| 613.23 | 7.41 | 7.41 |
| 589.16 | 6.32 | 6.32 |
| 601.22 | 7.26 | 7.26 |
| 613.23 | 7.41 | 7.41 |
| 587.19 | 6.87 | 6.87 |
| 601.22 | 7.26 | 7.26 |
| 589.21 | 6.65 | 6.65 |
| 613.23 | 7.41 | 7.41 |
| 601.17 | 6.40 | 6.40 |
| 631.20 | 6.33 | 6.33 |