Basic Information
ID: ALA4812574
Type: Binding
Description: Inhibition of BACE-1 (unknown origin) at 2 uM using Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-Dnp-OH as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by FRET assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Beta-secretase 1(ALA4822)
Document: ALA4811256
Inhibition of BACE-1 (unknown origin) at 2 uM using Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-Dnp-OH as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by FRET assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4812574
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 274.18 | ||
| 409.42 | 1.42 | 1.42 |
| 485.37 | ||
| 485.37 | ||
| 497.41 | ||
| 481.41 | ||
| 467.38 | ||
| 535.38 | ||
| 535.38 | ||
| 535.38 | ||
| 481.41 | ||
| 481.41 | ||
| 503.36 | ||
| 497.41 | ||
| 485.37 |