Basic Information
ID: ALA4812658
Type: Functional
Description: Antimalarial activity against drug-resistant Plasmodium falciparum 3D7 infected in human erythrocytes assessed as reduction in parasite growth measured after 72 hrs by SYBR Green method
Organism: Plasmodium falciparum
Strain: 3D7
Activity Charts
Bioactivity
Activity Types for Assay ALA4812658
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.30 | 5.85 | 5.85 |
| 323.32 | 3.22 | 3.22 |
| 340.32 | 3.96 | 3.96 |
| 284.31 | 3.23 | 3.23 |
| 446.43 | 3.13 | 3.13 |
| 417.44 | 4.34 | 4.34 |
| 403.41 | 4.03 | 4.03 |
| 391.28 | 3.57 | 3.57 |
| 366.40 | 4.40 | 4.40 |
| 323.37 | 3.49 | 3.49 |
| 392.39 | 3.25 | 3.25 |
| 383.37 | 2.47 | 2.47 |
| 359.35 | 3.69 | 3.69 |
| 386.41 | 3.34 | 3.34 |
| 406.41 | 4.42 | 4.42 |
| 417.40 | 3.50 | 3.50 |
| 421.40 | 4.17 | 4.17 |
| 404.40 | 3.43 | 3.43 |
| 406.41 | 4.68 | 4.68 |
| 385.30 | 3.37 | 3.37 |
| 420.40 | 2.64 | 2.64 |
| 377.37 | 3.54 | 3.54 |
| 385.34 | 3.91 | 3.91 |
| 391.40 | 3.55 | 3.55 |
| 392.43 | 4.39 | 4.39 |
| 403.41 | 4.03 | 4.03 |
| 378.41 | 3.21 | 3.21 |
| 418.38 | 4.94 | 4.94 |
| 431.42 | 4.68 | 4.68 |
| 403.41 | 4.03 | 4.03 |
| 427.39 | 3.97 | 3.97 |
| 412.80 | 3.59 | 3.59 |
| 367.33 | 2.70 | 2.70 |
| 378.36 | 2.94 | 2.94 |
| 417.39 | 3.99 | 3.99 |
| 368.36 | 2.19 | 2.19 |
| 457.25 | 4.57 | 4.57 |
| 403.37 | 2.81 | 2.81 |
| 418.42 | 4.60 | 4.60 |
| 341.31 | 3.36 | 3.36 |
| 341.36 | 3.55 | 3.55 |
| 421.40 | 4.17 | 4.17 |
| 335.41 | 3.36 | 3.36 |
| 416.41 | 4.11 | 4.11 |
| 456.26 | 5.17 | 5.17 |
| 339.32 | 2.46 | 2.46 |
| 403.37 | 3.49 | 3.49 |
| 445.41 | 3.20 | 3.20 |
| 391.40 | 3.85 | 3.85 |
| 305.38 | 3.35 | 3.35 |
| 416.41 | 4.11 | 4.11 |
| 417.39 | 4.67 | 4.67 |
| 334.30 | 2.78 | 2.78 |
| 374.44 | 4.25 | 4.25 |
| 361.47 | 2.06 | 2.06 |
| 391.39 | 4.72 | 4.72 |
| 349.36 | 3.71 | 3.71 |
| 392.38 | 4.12 | 4.12 |
| 391.40 | 3.85 | 3.85 |
| 395.36 | 3.68 | 3.68 |
| 393.37 | 3.51 | 3.51 |
| 456.27 | 4.30 | 4.30 |
| 366.34 | 2.27 | 2.27 |
| 389.30 | 4.78 | 4.78 |
| 377.37 | 3.54 | 3.54 |
| 415.42 | 4.71 | 4.71 |
| 417.39 | 4.67 | 4.67 |
| 402.38 | 3.41 | 3.41 |
| 354.33 | 1.93 | 1.93 |
| 347.34 | 3.75 | 3.75 |
| 422.41 | 4.26 | 4.26 |
| 416.41 | 4.41 | 4.41 |
| 390.29 | 4.18 | 4.18 |
| 352.32 | 2.01 | 2.01 |
| 418.38 | 4.07 | 4.07 |
| 402.38 | 3.41 | 3.41 |
| 428.42 | 3.90 | 3.90 |
| 345.35 | 2.80 | 2.80 |
| 460.46 | 3.39 | 3.39 |
| 352.37 | 2.53 | 2.53 |
| 347.34 | 4.38 | 4.38 |
| 392.39 | 2.95 | 2.95 |
| 396.35 | 3.08 | 3.08 |
| 416.40 | 5.28 | 5.28 |
| 390.29 | 4.18 | 4.18 |
| 348.33 | 3.78 | 3.78 |
| 405.42 | 3.86 | 3.86 |
| 434.42 | 2.90 | 2.90 |
| 394.39 | 4.12 | 4.12 |
| 363.34 | 2.98 | 2.98 |
| 341.33 | 2.44 | 2.44 |
| 348.33 | 3.78 | 3.78 |
| 392.39 | 3.25 | 3.25 |
| 284.31 | 3.23 | 3.23 |
| 408.38 | 3.61 | 3.61 |
| 295.34 | 2.95 | 2.95 |
| 357.76 | 3.87 | 3.87 |
| 369.34 | 1.82 | 1.82 |
| 417.39 | 4.18 | 4.18 |
| 391.40 | 3.85 | 3.85 |
| 383.32 | 4.58 | 4.58 |
| 428.42 | 3.90 | 3.90 |
| 352.31 | 4.25 | 4.25 |
| 383.27 | 3.76 | 3.76 |
| 384.31 | 3.98 | 3.98 |
| 377.29 | 3.56 | 3.56 |
| 384.31 | 3.98 | 3.98 |