Basic Information
ID: ALA4812856
Type: Binding
Description: Selectivity index, ratio of IC50 for displacement of [125-I]-[Sar1, Ile8] from recombinant human AT2R transfected in human HEK293 cells to IC50 for displacement of [125-I]-[Sar1, Ile8] from recombinant human AT1R transfected in human HEK293 cells
Format: BAO_0000219
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4811266
Selectivity index, ratio of IC50 for displacement of [125-I]-[Sar1, Ile8] from recombinant human AT2R transfected in human HEK293 cells to IC50 for displacement of [125-I]-[Sar1, Ile8] from recombinant human AT1R transfected in human HEK293 cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4812856
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1046.20 | ||
| 1123.32 | ||
| 1067.21 | ||
| 1072.23 | ||
| 969.15 | 1.14 | 1.14 |
| 952.13 | 1.04 | 1.04 |
| 1008.23 | ||
| 1084.24 | ||
| 969.15 | 1.14 | 1.14 |
| 1084.24 |