Basic Information
ID: ALA4813057
Type: Functional
Description: In vivo agonist activity at PPARalpha in high fat diet-induced nonalcoholic steatohepatitis C57BL/6J mouse model assessed as trans-repression of ApoC3 mRNA expression in liver administered at 3 mg/kg, po and measured after 24 hrs by quantitative real time PCR analysis
Format: BAO_0000218
Organism: Mus musculus
Strain: C57BL/6J
Target: Peroxisome proliferator-activated receptor alpha(ALA2128)
Document: ALA4811278
In vivo agonist activity at PPARalpha in high fat diet-induced nonalcoholic steatohepatitis C57BL/6J mouse model assessed as trans-repression of ApoC3 mRNA expression in liver administered at 3 mg/kg, po and measured after 24 hrs by quantitative real time PCR analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4813057
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 534.06 | 5.52 | 5.52 |
| 525.65 | 5.51 | 5.51 |
| 529.64 | 4.88 | 4.88 |
| 571.72 | 5.86 | 5.86 |
| 529.64 | 4.88 | 4.88 |
| 513.64 | 5.18 | 5.18 |
| 589.69 | 4.89 | 4.89 |
| 499.61 | 4.87 | 4.87 |
| 517.60 | 5.01 | 5.01 |