Basic Information
ID: ALA4813531
Type: Toxicity
Description: Selectivity index, ratio of IC50 for cytotoxicity against dog MDBK cells to IC50 for Trypanocidal activity against Trypanosoma congolense
Format: BAO_0000219
Target: ADMET(ALA612558)
Document: ALA4811303
Selectivity index, ratio of IC50 for cytotoxicity against dog MDBK cells to IC50 for Trypanocidal activity against Trypanosoma congolense: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4813531
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 295.34 | 4.33 | 4.33 |
| 311.34 | 4.03 | 4.03 |
| 387.44 | 5.60 | 5.60 |
| 281.31 | 4.03 | 4.03 |
| 281.31 | 4.03 | 4.03 |
| 281.31 | 4.03 | 4.03 |
| 312.33 | 3.43 | 3.43 |
| 338.36 | 3.98 | 3.98 |
| 395.37 | 3.78 | 3.78 |
| 331.37 | 5.18 | 5.18 |
| 285.32 | 3.59 | 3.59 |
| 328.39 | 3.90 | 3.90 |
| 326.31 | 3.93 | 3.93 |
| 337.33 | 3.86 | 3.86 |
| 269.26 | 3.13 | 3.13 |
| 341.36 | 4.04 | 4.04 |
| 341.36 | 4.04 | 4.04 |
| 281.31 | 4.03 | 4.03 |
| 281.31 | 4.03 | 4.03 |
| 341.36 | 4.01 | 4.01 |
| 371.39 | 4.05 | 4.05 |
| 297.31 | 3.73 | 3.73 |
| 311.34 | 4.03 | 4.03 |
| 341.36 | 4.04 | 4.04 |
| 311.34 | 4.03 | 4.03 |
| 253.26 | 3.42 | 3.42 |
| 327.41 | 4.50 | 4.50 |
| 285.25 | 2.83 | 2.83 |
| 341.36 | 4.04 | 4.04 |
| 341.36 | 4.04 | 4.04 |
| 286.31 | 2.99 | 2.99 |
| 311.34 | 4.03 | 4.03 |
| 324.38 | 4.09 | 4.09 |
| 269.26 | 3.13 | 3.13 |
| 311.34 | 4.03 | 4.03 |
| 269.26 | 3.13 | 3.13 |
| 401.42 | 4.06 | 4.06 |
| 311.34 | 4.03 | 4.03 |
| 311.34 | 4.03 | 4.03 |
| 325.36 | 4.42 | 4.42 |
| 296.33 | 3.61 | 3.61 |
| 453.40 | 3.71 | 3.71 |
| 339.39 | 4.81 | 4.81 |
| 395.37 | 3.78 | 3.78 |
| 311.34 | 4.03 | 4.03 |
| 371.39 | 4.05 | 4.05 |
| 281.31 | 4.03 | 4.03 |
| 270.24 | 2.52 | 2.52 |