Basic Information
ID: ALA4813853
Type: Binding
Description: Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9mer Nrf2 (unknown origin) incubated for 30 mins under shaking condition by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4813853
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 614.65 | 3.42 | 3.42 |
| 712.39 | 4.92 | 4.92 |
| 654.72 | 5.71 | 5.71 |
| 690.60 | 5.44 | 5.44 |
| 844.84 | 5.00 | 5.00 |
| 562.59 | 0.87 | 0.87 |
| 618.64 | 4.29 | 4.29 |
| 775.00 | 8.10 | 8.10 |
| 666.73 | 4.05 | 4.05 |
| 670.67 | 2.94 | 2.94 |
| 690.60 | 5.44 | 5.44 |
| 640.60 | 3.42 | 3.42 |
| 772.45 | 4.94 | 4.94 |
| 623.49 | 4.71 | 4.71 |
| 772.45 | 4.94 | 4.94 |
| 662.71 | 2.67 | 2.67 |
| 739.56 | 4.25 | 4.25 |
| 776.65 | 4.40 | 4.40 |
| 880.39 | 6.72 | 6.72 |
| 642.62 | 2.86 | 2.86 |
| 718.73 | 2.20 | 2.20 |
| 638.68 | 3.27 | 3.27 |
| 670.67 | 2.69 | 2.69 |
| 740.82 | 2.14 | 2.14 |
| 738.66 | 4.69 | 4.69 |
| 642.71 | 3.41 | 3.41 |