Inhibition of GGDPS in human RPMI-8226 cells assessed as disruption of farnesylation at 0.1 to 1 uM measured after 48 hrs by immunoblot analysis

Basic Information

ID: ALA4813906

Type: Binding

Description: Inhibition of GGDPS in human RPMI-8226 cells assessed as disruption of farnesylation at 0.1 to 1 uM measured after 48 hrs by immunoblot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: RPMI-8226

Target: Geranylgeranyl pyrophosphate synthetase(ALA4769)

Document: ALA4811322

Inhibition of GGDPS in human RPMI-8226 cells assessed as disruption of farnesylation at 0.1 to 1 uM measured after 48 hrs by immunoblot analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4813906

Inhibition

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
479.23	2.62	2.62
449.29	2.51	2.51
499.24	2.49	2.49

Parent Molecular Weight

ALogP

Polar Surface Area

479.23

2.62

449.29

2.51

499.24

2.49

Inhibition of GGDPS in human RPMI-8226 cells assessed as disruption of farnesylation at 0.1 to 1 uM measured after 48 hrs by immunoblot analysis

Basic Information

Activity Charts

Compound Summary