Basic Information
ID: ALA4814125
Type: Binding
Description: Inhibition of transactivation domain fused HOXA9 (unknown orgin) interaction with Luc-tagged DNA HOXA9 binding site (strand a-cgcgGTTCTCGATGATTTACGGATGATTTACTGATGATTTACCGATGATTTACAGATGATTTACGGATGATTTACGTGCT/strand b-ctagAGCACGTAAATCATCCGTAAATCATCTGTAAATCATCGGTAAATCATCAGTAAATCATCCGTAAATCATCGAGAAC) (unknown origin) co-transfected in human K562 cells assessed as reduction in HOXA9-mediated transactivation at 20 uM incubated for 48 hrs by luciferase assay
Format: BAO_0000219
Cell type: K562
Target: HOXA9 DNA binding site(ALA4845623)
Document: ALA4813909
Inhibition of transactivation domain fused HOXA9 (unknown orgin) interaction with Luc-tagged DNA HOXA9 binding site (strand a-cgcgGTTCTCGATGATTTACGGATGATTTACTGATGATTTACCGATGATTTACAGATGATTTACGGATGATTTACGTGCT/strand b-ctagAGCACGTAAATCATCCGTAAATCATCTGTAAATCATCGGTAAATCATCAGTAAATCATCCGTAAATCATCGAGAAC) (unknown origin) co-transfected in human K562 cells assessed as reduction in HOXA9-mediated transactivation at 20 uM incubated for 48 hrs by luciferase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4814125
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 360.45 | 3.53 | 3.53 |
| 354.42 | 3.47 | 3.47 |
| 345.36 | 3.32 | 3.32 |