Basic Information
ID: ALA4814126
Type: Binding
Description: Inhibition of transactivation domain fused HOXA9 (unknown orgin) interaction with Luc-tagged DNA HOXA9 binding site mutant (strand a-cgcgGTTCTCGATGCTGTCCGGATGCTGTCCTGATGCTGTCCCGATGCTGTCCAGATGCTGTCCGGATGCTGTCCGTGCT/strand b-ctagAGCACGGACAGCATCCGGACAGCATCTGGACAGCATCGGGACAGCATCAGGACAGCATCCGGACAGCATCGAGAAC) (unknown origin) co-transfected in human K562 cells assessed as reduction in HOXA9-mediated transactivation at 20 uM incubated for 48 hrs by luciferase assay
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA4814126
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 360.45 | 3.53 | 3.53 |
| 354.42 | 3.47 | 3.47 |
| 345.36 | 3.32 | 3.32 |