Basic Information
ID: ALA4814582
Type: Binding
Description: Binding affinity to wild type partial length human MAP4K5 (M1 to P297) expressed in Bacterial expression system assessed as residual activity at 100 nM measured by Kinomescan assay relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: Mitogen-activated protein kinase kinase kinase kinase 5(ALA4852)
Document: ALA4813918
Binding affinity to wild type partial length human MAP4K5 (M1 to P297) expressed in Bacterial expression system assessed as residual activity at 100 nM measured by Kinomescan assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4814582
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.93 | 5.54 | 5.54 |
| 272.31 | 1.92 | 1.92 |
| 457.46 | 3.68 | 3.68 |
| 403.41 | 3.21 | 3.21 |
| 455.49 | 4.89 | 4.89 |
| 445.45 | 4.48 | 4.48 |
| 443.89 | 4.62 | 4.62 |
| 517.54 | 4.34 | 4.34 |
| 471.94 | 5.41 | 5.41 |
| 503.50 | 5.04 | 5.04 |
| 523.95 | 6.19 | 6.19 |
| 489.93 | 5.54 | 5.54 |
| 487.49 | 3.69 | 3.69 |
| 533.94 | 5.27 | 5.27 |
| 486.53 | 4.94 | 4.94 |
| 488.40 | 5.92 | 5.92 |
| 517.99 | 6.32 | 6.32 |
| 453.88 | 6.13 | 6.13 |
| 507.92 | 5.49 | 5.49 |
| 485.51 | 4.90 | 4.90 |
| 453.95 | 5.27 | 5.27 |
| 537.98 | 6.33 | 6.33 |
| 469.51 | 5.20 | 5.20 |
| 503.96 | 5.93 | 5.93 |
| 527.58 | 5.21 | 5.21 |
| 461.52 | 4.95 | 4.95 |
| 469.51 | 5.20 | 5.20 |
| 473.48 | 5.03 | 5.03 |
| 489.93 | 5.54 | 5.54 |
| 467.98 | 5.57 | 5.57 |
| 555.97 | 6.47 | 6.47 |
| 475.90 | 5.15 | 5.15 |
| 499.54 | 5.21 | 5.21 |
| 555.97 | 6.47 | 6.47 |
| 555.97 | 6.47 | 6.47 |
| 563.99 | 5.92 | 5.92 |
| 532.01 | 6.71 | 6.71 |
| 550.01 | 6.20 | 6.20 |
| 552.00 | 6.64 | 6.64 |
| 515.54 | 4.91 | 4.91 |
| 491.47 | 5.17 | 5.17 |
| 513.52 | 4.66 | 4.66 |
| 486.53 | 4.94 | 4.94 |
| 505.93 | 4.78 | 4.78 |
| 578.02 | 5.97 | 5.97 |
| 471.94 | 5.41 | 5.41 |
| 543.90 | 6.09 | 6.09 |
| 473.48 | 5.03 | 5.03 |
| 485.51 | 4.90 | 4.90 |
| 485.51 | 4.90 | 4.90 |
| 515.54 | 4.91 | 4.91 |
| 471.94 | 5.41 | 5.41 |
| 517.56 | 5.99 | 5.99 |
| 473.48 | 5.03 | 5.03 |
| 519.99 | 6.20 | 6.20 |
| 507.92 | 5.68 | 5.68 |
| 457.46 | 3.68 | 3.68 |
| 499.50 | 4.62 | 4.62 |
| 547.97 | 5.32 | 5.32 |
| 457.46 | 3.68 | 3.68 |
| 461.88 | 4.76 | 4.76 |
| 277.28 | 3.19 | 3.19 |
| 469.51 | 5.20 | 5.20 |
| 552.00 | 6.38 | 6.38 |
| 487.50 | 5.34 | 5.34 |
| 471.94 | 5.41 | 5.41 |
| 552.00 | 6.64 | 6.64 |
| 519.96 | 5.55 | 5.55 |
| 497.53 | 4.56 | 4.56 |