Basic Information
ID: ALA4815322
Type: Binding
Description: Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assay
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4815322
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 612.63 | 3.63 | 3.63 |
| 388.21 | 4.33 | 4.33 |
| 386.22 | 3.90 | 3.90 |
| 385.23 | 3.61 | 3.61 |
| 461.09 | 3.81 | 3.81 |
| 356.19 | 3.88 | 3.88 |
| 400.24 | 4.20 | 4.20 |
| 520.35 | 5.47 | 5.47 |
| 414.67 | 4.30 | 4.30 |
| 500.37 | 5.25 | 5.25 |
| 476.34 | 5.77 | 5.77 |
| 370.22 | 4.19 | 4.19 |
| 356.23 | 4.50 | 4.50 |
| 441.30 | 3.70 | 3.70 |
| 410.28 | 4.75 | 4.75 |
| 445.09 | 4.10 | 4.10 |
| 465.75 | 3.53 | 3.53 |
| 386.22 | 3.90 | 3.90 |
| 369.23 | 3.59 | 3.59 |
| 351.22 | 4.36 | 4.36 |
| 457.34 | 5.94 | 5.94 |
| 412.30 | 4.99 | 4.99 |
| 408.27 | 3.75 | 3.75 |
| 535.84 | 3.90 | 3.90 |
| 475.36 | 5.17 | 5.17 |
| 520.35 | 5.47 | 5.47 |
| 514.39 | 5.32 | 5.32 |
| 494.33 | 5.91 | 5.91 |
| 482.37 | 5.83 | 5.83 |
| 370.22 | 4.19 | 4.19 |
| 398.27 | 4.60 | 4.60 |
| 573.89 | 3.46 | 3.46 |
| 394.25 | 3.67 | 3.67 |
| 460.11 | 3.52 | 3.52 |
| 482.37 | 5.83 | 5.83 |