Assay Report Card

Basic Information

ID: ALA4815607

Type: Binding

Description: Selectivity index, ratio of pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO cell membranes to pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO cell membranes

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
462.645.145.14
627.794.274.27
552.145.315.31
732.932.302.30
869.045.085.08
916.191.421.42
961.88-1.00-1.00
1230.981.731.73
1386.260.950.95
1473.21-1.27-1.27
1501.27-0.51-0.51
1358.200.170.17
1458.240.640.64
1060.971.911.91
1444.210.250.25
1459.19-1.66-1.66
1501.27-0.49-0.49
1358.200.170.17
1472.271.031.03
1416.16-0.39-0.39
1117.98-0.48-0.48
1487.24-0.88-0.88
1473.21-1.27-1.27
1372.230.560.56
1487.24-0.88-0.88
1458.240.640.64
1473.21-1.27-1.27
1258.210.560.56
1401.191.521.52
1344.18-0.22-0.22