Basic Information
ID: ALA4815608
Type: Binding
Description: Selectivity index, ratio of pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO cell membranes to pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO cell membranes
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4815608
Selectivity Index
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.64 | 5.14 | 5.14 |
| 627.79 | 4.27 | 4.27 |
| 552.14 | 5.31 | 5.31 |
| 732.93 | 2.30 | 2.30 |
| 869.04 | 5.08 | 5.08 |
| 916.19 | 1.42 | 1.42 |
| 1046.94 | 1.52 | 1.52 |
| 1160.06 | 0.55 | 0.55 |
| 1046.94 | 1.52 | 1.52 |
| 961.88 | -1.00 | -1.00 |
| 1301.15 | 0.92 | 0.92 |
| 1231.14 | 0.05 | 0.05 |
| 1230.98 | 1.73 | 1.73 |
| 1386.26 | 0.95 | 0.95 |
| 960.93 | 1.30 | 1.30 |
| 1514.31 | 0.55 | 0.55 |
| 1473.21 | -1.27 | -1.27 |
| 1329.20 | 1.88 | 1.88 |
| 1175.03 | -1.37 | -1.37 |
| 1470.21 | -0.21 | -0.21 |
| 1501.27 | -0.51 | -0.51 |
| 1358.20 | 0.17 | 0.17 |
| 1175.03 | -1.37 | -1.37 |
| 1458.24 | 0.64 | 0.64 |
| 1472.27 | 1.03 | 1.03 |
| 1060.97 | 1.91 | 1.91 |
| 1458.24 | 0.64 | 0.64 |
| 1444.21 | 0.25 | 0.25 |
| 903.88 | 2.19 | 2.19 |
| 1231.96 | 2.33 | 2.33 |
| 1459.19 | -1.66 | -1.66 |
| 1430.23 | 0.85 | 0.85 |
| 904.82 | -0.11 | -0.11 |
| 975.74 | 1.07 | 1.07 |
| 1315.18 | 1.49 | 1.49 |
| 1372.23 | 0.56 | 0.56 |
| 960.77 | 2.99 | 2.99 |
| 1501.27 | -0.49 | -0.49 |
| 1358.20 | 0.17 | 0.17 |
| 1571.36 | ||
| 1472.27 | 1.03 | 1.03 |
| 1330.15 | -0.61 | -0.61 |
| 1458.24 | 0.64 | 0.64 |
| 1416.16 | -0.39 | -0.39 |
| 635.52 | 1.46 | 1.46 |
| 1245.01 | 2.12 | 2.12 |
| 1244.10 | 1.81 | 1.81 |
| 1117.98 | -0.48 | -0.48 |
| 1487.24 | -0.88 | -0.88 |
| 1060.97 | 1.91 | 1.91 |
| 1358.20 | 0.17 | 0.17 |
| 1046.94 | 1.52 | 1.52 |
| 1473.21 | -1.27 | -1.27 |
| 1344.18 | -0.22 | -0.22 |
| 1173.06 | -0.33 | -0.33 |
| 1245.01 | 2.12 | 2.12 |
| 1372.23 | 0.56 | 0.56 |
| 1343.23 | 2.27 | 2.27 |
| 1487.24 | -0.88 | -0.88 |
| 1102.93 | 3.57 | 3.57 |
| 1458.24 | 0.64 | 0.64 |
| 1473.21 | -1.27 | -1.27 |
| 1060.97 | 1.91 | 1.91 |
| 989.77 | 1.46 | 1.46 |
| 1174.09 | 0.94 | 0.94 |
| 1315.18 | 1.44 | 1.44 |
| 874.76 | 2.90 | 2.90 |
| 1175.03 | -1.37 | -1.37 |
| 1501.27 | -0.51 | -0.51 |
| 1258.21 | 0.56 | 0.56 |
| 1401.19 | 1.52 | 1.52 |
| 1459.19 | -1.66 | -1.66 |
| 1484.24 | 0.18 | 0.18 |
| 1344.18 | -0.22 | -0.22 |
| 831.73 | 4.22 | 4.22 |
| 1086.93 | 4.03 | 4.03 |