Assay Report Card

Basic Information

ID: ALA4815609

Type: Binding

Description: Displacement of [3H]-NMS from human muscarinic M1 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition analysis

Organism: Homo sapiens

Cell type: CHO

Subcellular Fraction: Cell membrane

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
462.645.145.14
627.794.274.27
552.145.315.31
732.932.302.30
869.045.085.08
916.191.421.42
1046.941.521.52
1160.060.550.55
1046.941.521.52
961.88-1.00-1.00
1301.150.920.92
1231.140.050.05
1230.981.731.73
1386.260.950.95
960.931.301.30
1514.310.550.55
1473.21-1.27-1.27
1329.201.881.88
1175.03-1.37-1.37
1470.21-0.21-0.21
1501.27-0.51-0.51
1358.200.170.17
1175.03-1.37-1.37
1458.240.640.64
1472.271.031.03
1060.971.911.91
1458.240.640.64
1444.210.250.25
903.882.192.19
1231.962.332.33
1459.19-1.66-1.66
1430.230.850.85
904.82-0.11-0.11
975.741.071.07
1315.181.491.49
1372.230.560.56
960.772.992.99
1501.27-0.49-0.49
1358.200.170.17
1571.36
1472.271.031.03
1330.15-0.61-0.61
1458.240.640.64
1416.16-0.39-0.39
635.521.461.46
1245.012.122.12
1244.101.811.81
1117.98-0.48-0.48
1487.24-0.88-0.88
1060.971.911.91
1358.200.170.17
1046.941.521.52
1473.21-1.27-1.27
1344.18-0.22-0.22
1173.06-0.33-0.33
1245.012.122.12
1372.230.560.56
1343.232.272.27
1487.24-0.88-0.88
1102.933.573.57
1458.240.640.64
1473.21-1.27-1.27
1060.971.911.91
989.771.461.46
1174.090.940.94
1315.181.441.44
874.762.902.90
1175.03-1.37-1.37
1501.27-0.51-0.51
1258.210.560.56
1401.191.521.52
1459.19-1.66-1.66
1484.240.180.18
1344.18-0.22-0.22
831.734.224.22
1086.934.034.03