Antagonist activity at human muscarinic acetylcholine receptor M2 expressed in human HEK293T cells coexpressing NlucN-mini-Gsi assessed as inhibition ...

Basic Information

ID: ALA4815616

Type: Functional

Description: Antagonist activity at human muscarinic acetylcholine receptor M2 expressed in human HEK293T cells coexpressing NlucN-mini-Gsi assessed as inhibition of iperoxo-induced mini-Gsi recruitment by measuring equilibrium binding constant by nano-luciferase technique

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293T

Target:  Muscarinic acetylcholine receptor M2(ALA211)

Document:  ALA4813954

Antagonist activity at human muscarinic acetylcholine receptor M2 expressed in human HEK293T cells coexpressing NlucN-mini-Gsi assessed as inhibition of iperoxo-induced mini-Gsi recruitment by measuring equilibrium binding constant by nano-luciferase technique: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1473.21-1.27-1.27
1458.240.640.64
1459.19-1.66-1.66