Basic Information
ID: ALA4815829
Type: Binding
Description: Inhibition of recombinant His-tagged human TRKA (441 to 796 residues) expressed in baculovirus expression system using 5-FAM-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 1 hr followed by substrate addition in presence of ATP by mobility shift assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Nerve growth factor receptor Trk-A(ALA2815)
Document: ALA4813963
Inhibition of recombinant His-tagged human TRKA (441 to 796 residues) expressed in baculovirus expression system using 5-FAM-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 1 hr followed by substrate addition in presence of ATP by mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4815829
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 560.65 | 5.03 | 5.03 |
| 384.46 | 4.60 | 4.60 |
| 382.49 | 3.40 | 3.40 |
| 492.97 | 5.81 | 5.81 |
| 498.57 | 4.79 | 4.79 |
| 496.64 | 6.31 | 6.31 |
| 501.62 | 5.51 | 5.51 |
| 567.07 | 6.48 | 6.48 |
| 599.76 | 4.84 | 4.84 |
| 472.55 | 4.83 | 4.83 |
| 503.66 | 5.77 | 5.77 |
| 441.52 | 4.41 | 4.41 |
| 602.13 | 7.55 | 7.55 |
| 500.63 | 5.05 | 5.05 |
| 508.53 | 6.04 | 6.04 |
| 407.50 | 4.90 | 4.90 |
| 464.55 | 5.00 | 5.00 |
| 579.05 | 7.10 | 7.10 |
| 420.54 | 4.65 | 4.65 |
| 382.49 | 3.40 | 3.40 |
| 428.44 | 5.63 | 5.63 |