Basic Information
ID: ALA4815948
Type: Functional
Description: Induction of cell sensitization to imatinib in imatinib-resistant human K562 cells assessed as cell death at 10 uM incubated for 72 hrs in presence of 1 uM imatinib by PI staining based flow cytometry (Rvb = 19%)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: K562
Target: K562(ALA385)
Document: ALA4813967
Induction of cell sensitization to imatinib in imatinib-resistant human K562 cells assessed as cell death at 10 uM incubated for 72 hrs in presence of 1 uM imatinib by PI staining based flow cytometry (Rvb = 19%): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4815948
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 514.63 | 7.26 | 7.26 |
| 351.45 | 5.58 | 5.58 |
| 513.65 | 6.67 | 6.67 |
| 369.44 | 5.71 | 5.71 |
| 385.90 | 6.23 | 6.23 |
| 430.35 | 6.34 | 6.34 |
| 463.38 | 6.25 | 6.25 |
| 384.48 | 5.49 | 5.49 |
| 418.92 | 6.14 | 6.14 |
| 429.48 | 5.40 | 5.40 |
| 381.48 | 5.58 | 5.58 |
| 402.47 | 5.63 | 5.63 |
| 398.51 | 5.80 | 5.80 |
| 463.38 | 6.25 | 6.25 |
| 365.48 | 5.88 | 5.88 |
| 414.51 | 5.50 | 5.50 |
| 396.45 | 5.48 | 5.48 |
| 463.38 | 6.25 | 6.25 |