Basic Information
ID: ALA4816079
Type: Functional
Description: In vivo inhibition of HER2/EGFR dimerization in human A549 cells harbouring KRAS mutant/wild type EGFR xenografted in Foxn1nu/Foxn1+ mouse by measuring reduction in red fluorescence at 6 mg/kg, iv administered twice a week for 5 weeks by proximity ligation assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4816079
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1883.19 |