Assay Report Card

Basic Information

ID: ALA4816080

Type: Functional

Description: In vivo inhibition of HER2/HER3 dimerization in human A549 cells harbouring KRAS mutant/wild type EGFR xenografted in Foxn1nu/Foxn1+ mouse by measuring reduction in red fluorescence at 6 mg/kg, iv administered twice a week for 5 weeks by proximity ligation assay

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1883.19