ID: ALA4816080
Type: Functional
Description: In vivo inhibition of HER2/HER3 dimerization in human A549 cells harbouring KRAS mutant/wild type EGFR xenografted in Foxn1nu/Foxn1+ mouse by measuring reduction in red fluorescence at 6 mg/kg, iv administered twice a week for 5 weeks by proximity ligation assay
Organism: Mus musculus
Bioactivity
Activity Types for Assay ALA4816080
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
1883.19 |