Basic Information
ID: ALA4816214
Type: Binding
Description: Inhibition of IL-6 induced STAT3 transcriptional activity in human HepG2 cells incubated for 1 hr followed by stimulation with IL-6 for 5.5 hrs by luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Signal transducer and activator of transcription 3(ALA4026)
Document: ALA4813976
Inhibition of IL-6 induced STAT3 transcriptional activity in human HepG2 cells incubated for 1 hr followed by stimulation with IL-6 for 5.5 hrs by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4816214
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 533.72 | 7.09 | 7.09 |
| 303.30 | 0.82 | 0.82 |
| 593.77 | 6.88 | 6.88 |
| 242.23 | 1.55 | 1.55 |
| 607.80 | 7.41 | 7.41 |
| 568.16 | 7.74 | 7.74 |
| 551.69 | 5.85 | 5.85 |
| 634.82 | 6.32 | 6.32 |
| 593.77 | 7.11 | 7.11 |
| 575.80 | 8.04 | 8.04 |
| 551.71 | 7.22 | 7.22 |
| 579.74 | 6.63 | 6.63 |
| 563.75 | 7.09 | 7.09 |
| 563.75 | 7.09 | 7.09 |
| 601.72 | 8.10 | 8.10 |
| 534.64 | 5.17 | 5.17 |
| 595.74 | 5.87 | 5.87 |
| 551.71 | 7.22 | 7.22 |
| 608.79 | 5.78 | 5.78 |
| 577.77 | 7.40 | 7.40 |
| 593.77 | 7.11 | 7.11 |
| 547.75 | 7.39 | 7.39 |
| 558.73 | 6.96 | 6.96 |
| 547.75 | 7.39 | 7.39 |
| 593.77 | 7.11 | 7.11 |
| 535.62 | 5.14 | 5.14 |
| 612.62 | 7.85 | 7.85 |
| 561.77 | 7.70 | 7.70 |
| 561.77 | 7.65 | 7.65 |
| 607.80 | 7.41 | 7.41 |
| 568.16 | 7.74 | 7.74 |
| 650.82 | 5.55 | 5.55 |
| 569.70 | 7.36 | 7.36 |
| 547.75 | 7.39 | 7.39 |
| 547.75 | 7.39 | 7.39 |