Assay Report Card

Basic Information

ID: ALA4816988

Type: Functional

Description: In vivo inhibition of MDM2 in human MCF7 cells xenografted in BALB/c mouse assessed as increase in p53 expression at 25 to 50 mg/kg, ip administered once for 17 days by immunofluorescence analysis

Organism: Mus musculus

Strain: BALB/c

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
492.844.794.79