Assay Report Card

Basic Information

ID: ALA4817551

Type: Functional

Description: In vivo inhibition of KRAS signaling in Caenorhabditis elegans lin-1 L1 harboring let60 G13D mutant assessed as reduction in multi-vulva phenotype measured after 4 to 5 days culturing in buffer containing Escherichia coli OP50 by DIC/Nomarski microscopic analysis

Organism: Caenorhabditis elegans

Strain: lin-1 L1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
315.465.565.56
483.705.835.83
469.675.445.44
440.636.296.29