Basic Information
ID: ALA4817558
Type: Functional
Description: Antitumor activity human MIA PaCa-2 cells harboring KRAS mutation xenografted in nu/nu mouse assessed as induction of apoptosis by measuring increase in cleaved caspase 3 level in tumor at 1 to 5 mg/kg, ip administered once daily for 5 days with 2 days break by immunohistochemistry
Organism: Homo sapiens
Cell type: MIA PaCa-2
Activity Charts
Bioactivity
Activity Types for Assay ALA4817558
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 315.46 | 5.56 | 5.56 |
| 483.70 | 5.83 | 5.83 |
| 440.63 | 6.29 | 6.29 |