ID: ALA4817609
Type: Binding
Description: Inhibition of recombinant human His-tagged DCN1 (58 to 259 residues) expressed in Escherichia coli BL21 (DE3) assessed as reduction in DCN1/UBC12 interaction incubated for 30 mins by fluorescence polarization assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4817609
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
211.68 | 2.41 | 2.41 |
177.23 | 1.76 | 1.76 |
191.26 | 2.19 | 2.19 |
316.43 | 3.01 | 3.01 |
207.26 | 1.77 | 1.77 |
256.13 | 2.52 | 2.52 |
295.37 | 3.45 | 3.45 |
256.13 | 2.52 | 2.52 |
211.68 | 2.41 | 2.41 |
217.30 | 2.75 | 2.75 |
193.23 | 1.47 | 1.47 |
310.38 | 3.20 | 3.20 |
510.24 | 5.58 | 5.58 |
440.47 | 3.51 | 3.51 |
380.50 | 4.67 | 4.67 |
192.25 | 1.34 | 1.34 |
325.39 | 3.46 | 3.46 |
585.82 | 3.76 | 3.76 |
421.34 | 5.36 | 5.36 |
650.79 | 2.10 | 2.10 |
207.26 | 1.77 | 1.77 |
221.24 | 1.49 | 1.49 |
191.26 | 2.07 | 2.07 |
215.28 | 2.20 | 2.20 |
510.24 | 5.58 | 5.58 |
253.33 | 3.43 | 3.43 |
504.64 | 7.39 | 7.39 |
191.26 | 2.07 | 2.07 |
421.34 | 5.36 | 5.36 |
412.50 | 4.07 | 4.07 |
207.26 | 1.77 | 1.77 |
388.43 | 4.33 | 4.33 |
412.50 | 4.07 | 4.07 |
326.40 | 0.78 | 0.78 |
380.50 | 4.67 | 4.67 |
267.36 | 3.76 | 3.76 |
384.45 | 3.47 | 3.47 |
195.22 | 1.90 | 1.90 |
352.45 | 4.06 | 4.06 |
192.25 | 1.34 | 1.34 |