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Inhibition of BACE1 in human SH-SY5Y cells expressing APP assessed as reduction in Abeta40 by HTRF assay

Basic Information

ID: ALA4817668

Type: Binding

Description: Inhibition of BACE1 in human SH-SY5Y cells expressing APP assessed as reduction in Abeta40 by HTRF assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: SH-SY5Y

Target:  Beta-secretase 1(ALA4822)

Document:  ALA4814016

Inhibition of BACE1 in human SH-SY5Y cells expressing APP assessed as reduction in Abeta40 by HTRF assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4817668

IC50

Total(8)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
400.422.922.92
418.413.063.06
400.422.922.92
418.413.063.06
418.413.063.06
418.413.063.06
400.422.922.92
400.422.922.92
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