Basic Information
ID: ALA4817706
Type: ADME
Description: Ratio of drug level in Beagle dog cerebrospinal fluid after 3 hrs to IC50 for inhibition of BACE1 in human SH-SY5Y cells expressing APP assessed as reduction in Abeta40 by HTRF assay
Format: BAO_0000219
Target: ADMET(ALA612558)
Document: ALA4814016
Ratio of drug level in Beagle dog cerebrospinal fluid after 3 hrs to IC50 for inhibition of BACE1 in human SH-SY5Y cells expressing APP assessed as reduction in Abeta40 by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4817706
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 418.41 | 3.06 | 3.06 |