Assay Report Card

Basic Information

ID: ALA4818416

Type: Binding

Description: Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as effect on ACS in cell lysate pre-treated for 1 hr at 1 to 5 uM measured after 1 hr of stimulation by Western blot analysis

Organism: Mus musculus

Cell type: J774.A1

Subcellular Fraction: Lysate

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
321.384.034.03