Basic Information
ID: ALA4818719
Type: Binding
Description: Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate by Ellman's method
Format: BAO_0000357
Organism: Homo sapiens
Target: Acetylcholinesterase(ALA220)
Document: ALA4814070
Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate by Ellman's method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4818719
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 198.27 | 2.70 | 2.70 |
| 262.78 | 3.39 | 3.39 |
| 252.72 | 2.83 | 2.83 |
| 303.62 | 4.00 | 4.00 |
| 238.69 | 2.44 | 2.44 |
| 250.73 | 2.31 | 2.31 |
| 262.78 | 3.39 | 3.39 |
| 255.15 | 2.96 | 2.96 |
| 392.52 | 4.22 | 4.22 |
| 234.73 | 2.61 | 2.61 |
| 299.60 | 3.07 | 3.07 |
| 248.76 | 3.00 | 3.00 |
| 234.73 | 2.61 | 2.61 |
| 283.20 | 3.74 | 3.74 |
| 283.20 | 3.74 | 3.74 |
| 262.78 | 3.39 | 3.39 |
| 269.18 | 3.35 | 3.35 |
| 289.59 | 3.61 | 3.61 |
| 266.75 | 3.23 | 3.23 |
| 327.65 | 3.85 | 3.85 |
| 378.50 | 3.83 | 3.83 |
| 406.55 | 4.61 | 4.61 |
| 264.76 | 2.70 | 2.70 |
| 317.65 | 4.39 | 4.39 |
| 248.76 | 3.00 | 3.00 |
| 234.73 | 2.61 | 2.61 |
| 278.78 | 3.09 | 3.09 |
| 248.76 | 3.00 | 3.00 |
| 269.17 | 3.35 | 3.35 |
| 313.63 | 3.46 | 3.46 |