Basic Information
ID: ALA4818731
Type: Binding
Description: Inhibition of human GluN1a/GluN2B receptor expressed in HEK293 cells assessed as relative inhibition of glycine/glutamate-induced current measured at +40 mV holding potential by whole-cell patch clamp method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Nicotinic acetylcholine receptor alpha6/alpha3/beta4(ALA3137276)
Document: ALA4814070
Inhibition of human GluN1a/GluN2B receptor expressed in HEK293 cells assessed as relative inhibition of glycine/glutamate-induced current measured at +40 mV holding potential by whole-cell patch clamp method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4818731
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 198.27 | 2.70 | 2.70 |
| 250.73 | 2.31 | 2.31 |
| 255.15 | 2.96 | 2.96 |
| 299.60 | 3.07 | 3.07 |
| 248.76 | 3.00 | 3.00 |
| 283.20 | 3.74 | 3.74 |
| 264.76 | 2.70 | 2.70 |
| 313.63 | 3.46 | 3.46 |