Basic Information
ID: ALA4818907
Type: Binding
Description: Covalent inhibition of recombinant human GST-tagged BTK (2 to 659 end residues) expressed in baculovirus expression system assessed as inhibition constant using NH2-KKKAPFSWYLPEEG as substrate measured every 2 mins for 2 hrs in presence of ATP by microplate reader assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4818907
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 552.66 | 7.12 | 7.12 |
| 553.64 | 6.03 | 6.03 |
| 539.62 | 5.60 | 5.60 |
| 513.58 | 5.11 | 5.11 |
| 553.64 | 5.99 | 5.99 |
| 505.60 | 4.67 | 4.67 |
| 557.61 | 5.82 | 5.82 |
| 525.59 | 5.21 | 5.21 |
| 607.61 | 6.70 | 6.70 |
| 519.63 | 4.98 | 4.98 |
| 539.62 | 5.60 | 5.60 |
| 447.52 | 3.89 | 3.89 |
| 574.06 | 6.33 | 6.33 |
| 519.63 | 4.98 | 4.98 |
| 461.55 | 4.20 | 4.20 |