Basic Information
ID: ALA4818909
Type: Binding
Description: Inhibition of BTK in C57Bl/6 mouse splenocyte assessed as reduction in anti-IgM-induced CD69 expression incubated for 1 hr followed anti-IgM stimulation and measured after overnight by flow cytometry analysis
Organism: Mus musculus
Strain: C57Bl/6
Cell type: Splenocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA4818909
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 552.66 | 7.12 | 7.12 |
| 553.64 | 6.03 | 6.03 |
| 539.62 | 5.60 | 5.60 |
| 513.58 | 5.11 | 5.11 |
| 553.64 | 5.99 | 5.99 |
| 557.61 | 5.82 | 5.82 |
| 525.59 | 5.21 | 5.21 |
| 607.61 | 6.70 | 6.70 |
| 519.63 | 4.98 | 4.98 |
| 539.62 | 5.60 | 5.60 |
| 447.52 | 3.89 | 3.89 |
| 574.06 | 6.33 | 6.33 |
| 519.63 | 4.98 | 4.98 |
| 461.55 | 4.20 | 4.20 |