Basic Information
ID: ALA4819550
Type: Binding
Description: Inhibition of recombinant human PDE4D (83 to 416 residues) expressed in Escherichia coli BL21 (DE3) assessed as hydrolysis of [3H]-cAMP measured after 30 mins by Scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4819550
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.42 | 3.48 | 3.48 |
| 420.55 | 4.75 | 4.75 |
| 398.89 | 4.53 | 4.53 |
| 311.38 | 3.00 | 3.00 |
| 384.86 | 4.14 | 4.14 |
| 408.50 | 3.89 | 3.89 |
| 433.53 | 4.62 | 4.62 |
| 418.42 | 4.42 | 4.42 |
| 428.55 | 3.37 | 3.37 |
| 378.47 | 3.88 | 3.88 |
| 435.52 | 3.78 | 3.78 |
| 443.34 | 4.64 | 4.64 |
| 440.54 | 5.54 | 5.54 |
| 384.86 | 4.14 | 4.14 |
| 394.47 | 3.50 | 3.50 |
| 429.31 | 4.25 | 4.25 |
| 378.47 | 4.26 | 4.26 |
| 418.42 | 4.42 | 4.42 |
| 364.45 | 3.87 | 3.87 |
| 364.45 | 3.87 | 3.87 |
| 408.50 | 4.19 | 4.19 |
| 350.42 | 3.48 | 3.48 |
| 364.45 | 3.87 | 3.87 |
| 398.89 | 4.53 | 4.53 |
| 378.47 | 4.18 | 4.18 |
| 456.56 | 3.29 | 3.29 |
| 394.47 | 3.88 | 3.88 |
| 364.45 | 3.79 | 3.79 |
| 435.52 | 3.78 | 3.78 |
| 364.45 | 3.87 | 3.87 |
| 384.86 | 4.14 | 4.14 |
| 394.47 | 4.48 | 4.48 |
| 434.54 | 4.28 | 4.28 |
| 398.89 | 4.53 | 4.53 |
| 433.53 | 4.62 | 4.62 |
| 398.89 | 4.53 | 4.53 |
| 434.54 | 4.28 | 4.28 |
| 350.42 | 3.48 | 3.48 |
| 364.45 | 3.49 | 3.49 |
| 394.47 | 3.50 | 3.50 |
| 442.58 | 3.76 | 3.76 |
| 350.42 | 3.48 | 3.48 |
| 350.42 | 3.48 | 3.48 |
| 427.50 | 4.56 | 4.56 |
| 442.54 | 2.90 | 2.90 |
| 317.41 | 3.06 | 3.06 |
| 380.44 | 3.49 | 3.49 |
| 394.47 | 3.50 | 3.50 |
| 384.86 | 4.14 | 4.14 |
| 426.52 | 5.15 | 5.15 |
| 394.47 | 3.80 | 3.80 |
| 426.52 | 5.05 | 5.05 |