Basic Information
ID: ALA4819633
Type: Binding
Description: Inhibition of alpha-tubulin polymerization in human HEp-2 cells assessed as disintegration of microtubule network at 0.3 to 30 uM measured after 3 hrs by DAPI staining based immunoflourescence method relative to vincristine
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEp-2
Target: Unchecked(ALA612545)
Document: ALA4818996
Inhibition of alpha-tubulin polymerization in human HEp-2 cells assessed as disintegration of microtubule network at 0.3 to 30 uM measured after 3 hrs by DAPI staining based immunoflourescence method relative to vincristine: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4819633
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.47 | 4.69 | 4.69 |
| 344.46 | 4.82 | 4.82 |