Assay Report Card

Basic Information

ID: ALA4819635

Type: Binding

Description: Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 mins followed by addition of ATP and measured after 4 mins by Scintillation counting method

Organism: Escherichia coli

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
521.64-1.14-1.14
582.68-0.52-0.52
498.56-1.03-1.03
525.630.210.21
526.62-0.39-0.39
611.72-0.45-0.45
609.621.111.11
561.751.451.45
595.761.951.95
478.57-2.00-2.00
568.70-0.16-0.16
553.680.330.33