Assay Report Card

Basic Information

ID: ALA4819957

Type: Binding

Description: Protac activity at CRBN/CDK9 in human MV4-11 cells assessed as induction of CDK9 degradation at 250 nM pretreated for 2 hrs with proteasome inhibitor, MG132 followed by incubation with compound for 6 hrs by western blot analysis

Organism: Homo sapiens

Cell type: MV4-11

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
855.954.914.91