Basic Information
ID: ALA4819990
Type: Binding
Description: Inhibition of BTK in human Ramos cells assessed as reduction of IgM stimulated PLCgamma2 (Y1217) phosphorylation at 1 to 5 uM measured after 24 hrs by western blot assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Ramos
Target: Tyrosine-protein kinase BTK(ALA5251)
Document: ALA4819006
Inhibition of BTK in human Ramos cells assessed as reduction of IgM stimulated PLCgamma2 (Y1217) phosphorylation at 1 to 5 uM measured after 24 hrs by western blot assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4819990
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 588.71 | 6.70 | 6.70 |
| 538.65 | 5.67 | 5.67 |
| 572.63 | 5.28 | 5.28 |
| 533.59 | 4.80 | 4.80 |