Assay Report Card

Basic Information

ID: ALA4820003

Type: Binding

Description: Antagonist activity at recombinant 6His-tagged thrombin cleavage site of FimH Lectin domain R98A mutant expressed in Escherichia coli HM125 assessed as dissociation constant measured after 24 hrs by fluorescence polarization assay

Organism: Escherichia coli

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
278.35-0.23-0.23
307.31-1.08-1.08
395.37-1.53-1.53
395.37-1.53-1.53
479.530.810.81
381.34-1.62-1.62
465.500.420.42
493.561.201.20
451.480.030.03
451.480.330.33
381.34-1.62-1.62
409.40-0.84-0.84
479.530.810.81
409.40-0.84-0.84
437.45-0.06-0.06
437.45-0.06-0.06
423.42-0.45-0.45
437.45-0.36-0.36
465.500.420.42
465.500.720.72
493.561.201.20
423.42-0.75-0.75
451.480.030.03
465.500.720.72
451.480.330.33
423.42-0.45-0.45