Basic Information
ID: ALA4820059
Type: Binding
Description: Inhibition of ASK1 in human HEK293 cells transfected with AP1 assessed as inhibition of AP1-induced luciferase activity at 10 uM preincubated for 1 hr followed by PMA stimulation and measured after 6 hrs by luciferase reporter assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4820059
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.50 | 4.68 | 4.68 |
| 347.38 | 3.92 | 3.92 |
| 496.58 | 4.87 | 4.87 |
| 360.42 | 3.96 | 3.96 |
| 362.39 | 2.63 | 2.63 |
| 346.39 | 3.65 | 3.65 |
| 380.84 | 4.31 | 4.31 |
| 360.42 | 3.96 | 3.96 |
| 412.46 | 4.04 | 4.04 |
| 484.56 | 5.07 | 5.07 |
| 347.38 | 3.05 | 3.05 |
| 426.48 | 4.06 | 4.06 |
| 376.42 | 3.66 | 3.66 |
| 423.48 | 4.72 | 4.72 |
| 412.46 | 4.04 | 4.04 |
| 412.46 | 4.04 | 4.04 |